Page 104 - Advanced echocardiography in characterization and management of patients with secondary mitral regurgitation
P. 104

Chapter five. MV geometry: The COAPT Trial
Table 3. Impact of Baseline Echocardiographic Parameters on Post-MitraClip Severity of Mitral Regurgitation at 30 Days.
  MR grade at 30 days
  Grade 0 or 1+
Mitral valve geometrical measurements
Grade 2+
3.53 ± 0.34 (49)
3.24 ± 0.30 (48)
4.01 ± 0.44 (47)
10.2 ± 2.5 (48) 2.16 ± 0.69 (48) 2.25 ± 0.43 (47)
1.34 ± 0.23 (39)
1/38 (2.6) 2/38 (5.3) 10/38 (26.3) 16/38 (42.1) 8/38 (21.1) 0/38 (0.0)
1/38 (2.6)
4.25 ± 0.58 (27)
3.88 ± 0.49 (24)
3.62 ± 0.50 (17) 33 ± 6 (22)
20 ± 6 (47)
41 ± 8 (45)
19/54 (35.2) 35/54 (64.8)
Grade 3+ or 4+ P-value
3.66 ± 0.41 (18) 0.50 3.36 ± 0.34 (20) 0.44
4.08 ± 0.38 (20) 0.68
9.5 ± 1.5 (20) 0.48 2.26 ± 0.59 (20) 0.71 2.37 ± 0.37 (19) 0.47
1.29 ± 0.17 (19) 0.70
0.05
0/17 (0.0)
2/17 (11.8)
3/17 (17.6)
8/17 (47.1)
1/17 (5.9)
3/17 (17.6)
0/17 (0.0)
4.61 ± 0.50 (10) 0.08
3.91 ± 0.66 (12) 0.24
4.02 ± 0.72 (7) 0.34 28 ± 8 (9) 0.13 20 ± 7 (17) 0.11 41 ± 11 (14) 0.04
  Intercommissural mitral valve annulus diameter (cm)
Anteroposterior mitral valve annulus diameter (cm)
Coaptation to septum distance (cm)
Tenting height (mm) Tenting area (cm2)
Anterior mitral valve leaflet length (cm)
Posterior mitral valve leaflet length (cm)
Tethering location, n/N (%)
None P1 P1-P2 P2 P2-P3 P3
All
Posterior papillary muscle to annulus distance (cm; 4CH view)
Posterior papillary muscle to annulus distance (cm; 2CH view)
Anterior papillary muscle to annulus distance (cm)
Basal mitral anterior leaflet angle (o)
Distal mitral anterior leaflet angle (o)
Mitral posterior leaflet angle (o)
3.56 ± 0.42 (188)
3.26 ± 0.40 (188)
4.07 ± 0.44 (182)
9.8 ± 2.5 (186) 2.13 ± 0.71 (186) 2.26 ± 0.34 (174)
1.34 ± 0.25 (141)
5/149 (3.4) 18/149 (12.1) 43/149 (28.9) 61/149 (40.9) 18/149 (12.1) 4/149 (2.7) 0/149 (0.0) 4.17 ± 0.61 (95)
4.07 ± 0.55 (83)
3.84 ± 0.69 (77) 31 ± 6 (81)
18 ± 6 (164)
37 ± 9 (161)
Mitral valve regurgitation quantification
Mitral regurgitation, n/N (%)
(3+) Moderate to severe (4+) Severe
0.0001
116/199 (58.3) 83/199 (41.7)
4/21 (19.0) 17/21 (81.0)
  102
































   102   103   104   105   106