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Content Chapter 1 Chapter 2
Chapter 3
Chapter 4 Chapter 5
Chapter 6 Chapter 7 Chapter 8
Chapter 9
Chapter 10 Chapter 11
General Introduction 9
Management of lumbar spinal stenosis: 15 a survey among Dutch spine surgeons
Effectiveness of interspinous implant surgery: 31 a systematic review and meta-analysis
The Felix Trial: design and protocol. 51
The Felix Trial: clinical results after one year and 69 subgroup analysis
The Felix Trial: clinical results after two years 93
The Felix Trial: cost-utility analysis 113
Preoperative MR imaging in patients with intermittent 129 neurogenic claudication: relevance for diagnosis and
prognosis
General discussion – scientific evaluation of spinal 149 implants; an ethical necessity
Summary 161 Samenvatting 167
List of publications 172 About the author 174 Acknowledgements 175


































































































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