Page 75 - When surgery alone won’t cut it - Valerie Maureen Monpellier

ferences from 15 to 24 follow-up points in HRQoL were analyzed with paired sample T-tests. A regression analysis was performed to examine the relationship between BMI at baseline (BL), 15 months (15M) and 24 months (24M) and HRQoL total scores. Lin- ear regression was also performed to study the relationship between weight change (%TWL) and HRQOL-scores at 15 and at 24-month follow-up. In addition, change in HRQoL (ΔHRQoL) from baseline to both follow-up moments, 15 and 24 months, was calculated. And two new variables were created, ΔHRQoL15 and ΔHRQoL24:
ΔHRQoL15 =
ΔHRQoL24 =
15-month HRQoL score – baseline HRQoL score maximum HRQoL score
24-month HRQoL score – baseline HRQoL score maximum HRQoL score
The relationship of ΔHRQoL and %TWL at both follow-up moments was first exam- ined with a bivariate analysis for total scores. Secondly a multiple regression was performed adjusting for baseline BMI, gender, age and comorbidities (diabetes melo- litus, hypertension, obstructive sleep apnoea syndrome, hypercholesterolemia and osteoarthritis).
All statistical analysis was performed using the SPSS (version 23) statistical software. In all analysis a p value <0.05 was considered statistically significant.
RESULTS
Study population
The study population consisted of 2,137 patients, 425 patients were excluded be- cause of insufficient data. All patients had a follow-up longer than 15 months; in 44 patients (2.1%) no weight loss data was available at 15 months. Follow-up was longer than 24 months in 1,411 patients, in 23.5% (n=332) no weight loss data were avail- able.
Preoperative RAND-36 scores were available in 2,133 patients, at 15 months for 2074 patients and at 24 months for 1036 patients. For IWQOL-lite results of 2,130 patients were available preoperatively, at 15 months there were 1,953 results and at 24 months 612 results.
Mean age was 45.8 years and 82.5% of the population was female (Table 1). Mean baseline BMI was 44.5 kg/m2 (±5.8). At 15M follow-up, mean BMI was 30.7 kg/m2 (±5.1) and TWL was 31.0%; at 24M mean BMI was 30.7 kg/m2 (±5.2) and mean TWL was 31.1%.
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