Page 46 - Functional impairment and cues for rehabilitation of head and neck cancer patients -

Chapter 2
Appendix 5 Self-reported swallowing and secondary functional outcomes at 4- and 12-month follow-up grouped by intended surgery and RT. Poisson regression analysis comparing RT to surgery (reference).
4-month follow-up
12-month follow-up
Number of participants (%)
Regression analysis
Number of participants (%)
Regression analysis
Surgery (n = 150)
RT
(n = 150)
RR (95% CI)
P
value
Surgery (n = 150)
RT
(n = 150)
RR (95% CI)
P
value
Self-reported swallowing outcomes (from EORTC-QLQ-H&N35)
Problems swallowing liquids, pureed or solid food
Problems swallowing liquids
Problems swallowing pureed food
Problems swallowing solid food
No 55 Yes 29
Unknown 66
No 73 Yes 12
Unknown 65
No 70 Yes 14
Unknown 66
No 55 Yes 27 Unknown 68
(66) (35)
(86) (14)
(83) (17)
(67) (33)
41 (45) 50 (55)
59
77 (84) 15 (16)
58
68 (76) 21 (24)
61
42 (46) 50 (54) 58
MA: 1.6 (1.0–2.5)
A: 1.3 (0.8–2.0)
MA: 1.4 (0.5–4.0)
A: 1.1 (0.4–3.1)
MA: 2.7 (1.0–7.5)
A: 2.0 (0.8–5.2)
MA: 1.6 (1.0–2.7)
A: 1.3 (0.8–2.1)
.051 .249
.493 .869
.062 .157
.040 .287
.039 .093
.767 .766
.138 .311
.049 .137
64 (77) 19 (23)
67
79 (85) 4 (5)
67
80 (96) 3 (4)
67
65 (78) 18 (22) 67
67 (83) 14 (17)
69
80 (96) 3 (4)
67
62 (79) 17 (22)
71
79 (95) 4 (5) 67
51 (65) 28 (35)
71
74 (93) 6 (8)
70
71 (90) 8 (10)
71
52 (65) 28 (35) 70
52 (68) 24 (32)
74
75 (96) 3 (4)
72
61 (77) 18 (23)
71
68 (86) 11 (14) 71
MA: 1.3 .362 (0.7–2.3)
A: 1.3 .277 (0.8–2.3)
MA: 1.9 .167 (0.4–9.8)
A: 1.6 .628 (0.2–11.1)
MA: 2.4 .284 (0.5–12.4)
A: 2.1 .361 (0.4–10.3)
MA: 1.3 .388 (0.7–2.3)
A: 1.3 .308 (0.8–2.2)
MA: 2.0 .055 (1.0–4.0)
A: 2.1 .051 (1.0–4.6)
MA: 1.5 .747 (0.1–14.3)
NA
MA: 1.1 .715 (0.6–2.2)
A: 1.5 .319 (0.7–3.1)
MA: 2.1 .176 (0.7–6.8)
A: 2.7 .145 (0.7–10.3)
Secondary functional outcomes (from EORTC-QLQ-H&N35)
Weight loss
Tube feeding
Pain mouth, jaw or throat
Coughing
No 54 Yes 31
Unknown 65
No 74 Yes 13
Unknown 63
No 50 Yes 34
Unknown 66
(64) (37)
(85) (15)
(60) (41)
42 (46) 49 (54)
59
75 (81) 18 (19)
57
50 (54) 42 (46)
58
78 (85) 14 (15) 58
MA: 1.6 (1.0–2.6)
A: 1.5 (0.9–2.4)
MA: 1.1 (0.5–2.6)
A: 0.9 (0.4–2.2)
MA: 1.4 (0.9–2.3)
A: 1.3 (0.8–2.0)
MA: 3.3 (1.0–11.0)
A: 2.3 (0.8–7.2)
No 76 Yes 6 (7) Unknown 68
(93)
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