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Appendix 3 Self-reported swallowing outcomes and secondary comparisons between group with Chi-square tests.
functional outcomes at baseline. P values shown for
Swallowing function after treatment for early-stage OPC
Intended treatment Number of participants (%)
P value
Intended and received treatment
Number of participants (%)
P
value
Surgery (n = 150)
RT
(n = 150)
Surgery (n = 66)
RT (n= 126)
Surgery and received surgery + (C)RT
(n = 78)
Self-reported swallowing outcomes (from EORTC-QLQ-H&N35)
2
Problems swallowing No
33 (75) 11 (25) 22
37 (82) 8 (18) 21
40 (91) 4 (9) 22
36 (80) 9 (20) 21
34 (77) 10 (23) 22
45 (100) 0 (0)
21
27 (63)
16 (37) 23
41 (91) 4 (9) 21
40 (89) 5 (11) 21
34 (76) 11 (24) 21
73 (79) 19 (21) 34
83 (89) 10 (11) 33
83 (90) 9 (10) 34
75 (80) 19 (20) 32
68 (76) 22 (24) 36
89 (96) 4 (4) 33
57 (61)
36 (39) 33
90 (96) 4 (4) 32
87 (93) 7 (7) 32
71 (76) 23 (25) 32
38 (73) .831 14 (27)
26
43 (83) .952 9 (17)
26
45 (87) .503 7 (14)
26
39 (75) .558 13 (25)
26
42 (79) .814 11 (21)
25
53 (100) NA 0 (0)
25
34 (67) .695
17 (33) 27
50 (96) .304 2 (4)
26
46 (87) .752 7 (13)
25
40 (77) .875 12 (23)
26
liquids, pureed or solid food
73 (73) Yes 27 (27)
Unknown 50
84 (75) 28 (25) 38
98 (87) 15 (13) 37
100 (89) 12 (11) 38
86 (75) 28 (25) 36
.740
.358
.768
.891
Problems swallowing No
liquids
83 (82) Yes 18 (18)
Unknown 49
Problems swallowing No
pureed food
88 (88) Yes 12 (12)
Unknown 50
Problems swallowing No
77 (76)
solid food
Yes 24 Unknown 49
(24)
Secondary functional outcomes (from EORTC-QLQ-H&N35)
Weight loss
Tube feeding
Pain mouth, jaw or throat
Coughing
Trouble opening mouth
Dry mouth
No 79 (78) Yes 22 (22) Unknown 49
No 101 (99) Yes 1 (1) Unknown 48
No 62 (63)
Yes 36 (37) Unknown 52
No 95 (94) Yes 6 (6) Unknown 49
78 (72) 31 (28) 41
108 (96) 5 (4)
37
67 (59)
46 (41) 37
108 (96) 5 (4)
37
104 (91) 10 (9) 36
86 (75) 28 (25) 36
.267
.126
.555
.616
.468
.891
No 90 Yes 12 Unknown 48
No 77 Yes 24 Unknown 49
(88) (12)
(76) (24)
41