Page 109 - Organ motion in children for high-precision radiotherapy - Sophie Huijskens

dosimetric impact should be interpreted with caution. Nevertheless, as recently recommended by the Paediatric Radiation Oncology Society (PROS) [34], consensus needs to be reached towards accurate margin definition in pediatric radiotherapy. With this study, we take another step closer towards developing guidelines for the appropriate approach to define accurate safety margins in pediatric radiotherapy.
5.5 | Conclusions
In conclusion, these present results indicate that for children, a single pre-treatment measurement of respiratory-induced motion with 4DCT could be effective and could provide a good representation for intrafractional motion during radiotherapy. Moreover, large variation in amplitude and cycle time in both children and adults, confirms that 4DCT could be used for a more precise and individualized approach in pediatric radiotherapy, thereby aiming for more accurate safety margins and minimizing the risk of adverse events.
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