Page 64 - Comprehensive treatment of patients with glucocorticoid-dependent severe asthma
P. 64
Chapter 3
Figure 1. Prevalence of anxiety and depressive symptoms 25
20 15 10
5 0
anxiety
depression
Figure 1. Percentage of patients with high anxiety and depression symptoms in severe prednisone-dependent asthma as compared to patients with severe non-prednisone dependent asthma and mild asthma.
Table 2. Psychological Questionnaire scores for patients with severe prednisone-dependent, moderate- severe and mild-moderate asthma
HADS Anxiety Depression
NEO-FFI Neuroticism Extraversion
Openness Agreeableness Conscientiousness
Severe prednisone- dependent
n=67
6.2 (4.4) 4.5 (3.6) 33.7 (5.6) 38.6 (4.7) 37.4 (4.2) 35 (4.3) 40.2 (4.3)
Severe
non prednisone- dependent
n=47
4.8 (3.6) 2.5 (2.4) 32.2 (3.9) 39 (4.1) 36.4 (4.2) 36 (5.2) 39.9 (4.1)
Mild- P-value moderate
n=73
5.0 (2.9) 0.07 3.4 (2.5) 0.002 31.8 (2.8) 0.07 39 (3.6) 0.8 37.4 (3.3) 0.3 35.8 (4.5) 0.4 40.8 (3.1) 0.4
Depression Scale; NEO-FFI,
Footnote table 2: Values expressed in mean (SD). HADS, Hospital Anxiety and Neo-Five-Factor Inventory.
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mild
severe
prednisone