Page 118 - Bladder Dysfunction in the Context of the Bladder-Brain Connection - Ilse Groenendijk.pdf

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Chapter 6
ABSTRACT
Aims: The OAB-q SF evaluates both symptom bother and health-related quality of life in patients with overactive bladder, a highly prevalent disease. The objective of this study was to translate and validate a Dutch version of the OAB-q SF.
Methods: The translation into Dutch and validation process of the OAB-q SF was performed according to standardized guidelines. Patients with overactive bladder who visited the department of Urology outpatient clinic completed the questionnaires OAB- q SF, EQ-5D-5L, UDI-6 and the ICIQ-OAB at baseline (test) and two weeks later (retest). A reference group from the department of Allergology outpatient clinic completed the same questionnaires once. The evaluated measurement properties included content validity, internal consistency, reproducibility, criterion validity and construct validity.
Results: Fifty-two patients were included in the study group and 51 references were included. The content validity was adequate and the internal consistency was excel- lent (Cronbach’s alpha > 0.80). The reproducibility was good with intraclass correlation coefficients higher than 0.70. Patient’s OAB-q SF scores were moderately to strongly correlated with the UDI-6, ICIQ-OAB and the EQ-5D-5L confirming the criterion validity. A good construct validity was demonstrated with significant higher scores of the OAB-q SF score in patients compared to references.
Conclusions: The Dutch OAB-q SF is a reliable and valid measure to evaluate symptom bother and health-related quality of life in patients with overactive bladder.
Keywords: Patient Reported Outcome, Questionnaire, Overactive Bladder, Urgency, OAB-q SF, Validation, Translation