Page 112 - Bladder Dysfunction in the Context of the Bladder-Brain Connection - Ilse Groenendijk.pdf
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Chapter 5
the cause that PNE is a less sensitive screening method than FSTLP.30 In our hospital, OAB patients first undergo a PNE, in case this is inconclusive, a FSTLP is conducted. The influ- ence of this on our study results is considered minimal, since all four patients reported to feel stimulation during the UDS 2 at the same location as during placement of the PNE lead. Moreover, the stimulation parameters used during PNE and FSTLP were the same (frequency 14 Hz and pulse width 210 μs). Ultimately, for this study, it was merely of relevance whether or not the patient is a responder to sacral neuromodulation in general. The method of testing is of secondary importance.
In conclusion, this study suggests that there are no acute effects of SNM on conven- tional UDS parameters. More studies are needed to confirm this finding and further elucidate the role of factors such as gender, age and etiology of OAB.
