Page 66 - Effects and Efficacy of (Laparoscopic) Gastrostomy Placement in Children - Josephine Franken

investigated with the Chi-Squared test or, in case of small-expected numbers, with the Fisher’s exact test. Correlations of continuous data were investigated with the Pearson’s correlation coefficient. Missing values were imputed using multiple imputation with 20 imputations. Descriptive statistics are reported for the original data; examination and testing of relations between variables was performed on the multiply imputed data.
Gastrostomy failure was defined as feeding intolerance or leakage at the gastrostomy site. Feeding intolerance was determined with the questionnaire that was filled out by parents scoring the vomiting symptoms of their child on a frequency scale (0–7 days a week) and a severity scale (0–7; Table 1). Patients with at least daily and moderately severe vomiting or at least weakly and severe vomiting (Grade 2 or 3) were considered feeding intolerant. Leakage at the gastrostomy site was determined by the indication for (re)admission or gastrojejunostomy placement. To identify parameters predictive of gastrostomy failure, logistic regression analysis was performed. Potential risk factors were: age, neurologic impairment, preoperative GE, acid exposure time and symptomatic GER.
To identify parameters predictive of postoperative GE, multiple linear regression analysis was performed. Variables included in the analysis were: age, NI, preoperative GE, acid exposure time and symptomatic GER. Statistical significance was defined by p-values of less than 0.05. All analyses were performed using SPSS 22.0 statistical package (IBM, USA).
Table 1. scoring system that combines severity and frequency of symptoms of feeding intoler- ance.
ResULTs
A total of 50 patients were included with a median age of 3.4 years (1.4 – 5.6). Indication for gastrostomy was insufficient oral caloric intake in 47 patients. The remaining 3 patients received a gastrostomy for administering laxatives in chronic obstipation. The main underlying pathologies were neurological disorder (68%) and cystic fibrosis (8%). Patient characteristics are described in Table 2.
severe
Moderate
Mild
Absent
Daily
Grade 3
Grade 2
Grade 1
Grade 0
Weekly
Grade 2
Grade 1
Grade 1
Grade 0
Monthly
Grade 1
Grade 1
Grade 1
Grade 0
infrequent
Grade 1
Grade 1
Grade 1
Grade 0
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