Page 78 - DECISION-MAKING IN SEVERE TRAUMATIC BRAIN INJURY PATIENT OUTCOME, HOSPITAL COSTS, AND RESEARCH PRACTICE

Chapter 3
Table 1: Study details & results
# Study info a
Purpose
Determine predictors in paediatric s-TBI patients
Determine the cost-effectiveness of treatment strategies in s-TBI patients
Assign costs to treatment of surgically treated patients with TBI
Acute treatment costs for TBI
Cost-effectiveness of ICP monitoring in paediatric s-TBI patients
Study Design
Retrospective cohort study
Decision- analytical model
Retrospective cohort study
Prospective observational multicentre study
Decision-tree model
Patient (N)
136 s-TBI N/A
26 s-TBI
2500 s-TBI
Based on 33 s-TBI patients
Definition of TBI
Non-penetrating head injury, not further specified
TBI, not further specified
ICD-10 codes
TBI diagnosis was made
by admitting neurosurgeons or ER physicians and confirmed by CT
TBI, not further specified
Severity definition
GCS≤8 at admission to ED
GCS≤8 and motor component of ≤5 at admission
GCS3-8 on presentation
GCS≤8 at admission
GCS3-8
21 -
- 2001
22 -
Whitmore 58
White 37
- 1991-1995
- USA
- 2012
- N/A
- USA
- 2015-2016
- Malaysia
23 -
- 2018
24 -
- 201)
25 -
Zapata-
You50
Yuan 53
- 2004
- China
Vazquez 38
- 2017
- N/A
- Mexico
This table shows the main study characteristics and results
AIS, Abbreviated Injury Scale; ARDS, Adult Respiratory Distress Syndrome; BTF, Brain Trauma Foundation; CCR, Cost to Charge Ratio; CEA, Cost Effectiveness Analysis; CT, Computed Tomography; c-TBI, critical TBI; DRG, Diagnosis Related Groups; ED: Emergency Department; EMS, Emergency Medical Services; ET, Early Tracheostomy; GCS, Glasgow Coma Scale; HCUP-KID, Healthcare Cost and Utilization Project - Kids’ Inpatient Database; HMO, Health Maintenance Organization; ICD-10, International Classification of Diseases, 10th Revision; ICD-9-CM, International Classification of Diseases, Ninth Revision; ICP, Intracranial Pressure; ICU, Intensive Care Unit; LOS, Length of Stay; LT, Late Tracheostomy; N/A, not applicable; N, Number; NIS, National Inpatient Sample; NP, Not provided; s-TBI, severe Traumatic Brain Injury; TBI, Traumatic Brain Injury; vs-TBI, very severe Traumatic Brain Injury; Y, Year
Legend:
a Name first author [reference #] - year of publication - Cohort inclusion period - Study country.
b GDP per capita from year of currency and converted to $ 2015.
c When available, severity defined by GCS was further specified by adding the mean GCS ± SD. (Unless stated otherwise)
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