Page 193 - DECISION-MAKING IN SEVERE TRAUMATIC BRAIN INJURY PATIENT OUTCOME, HOSPITAL COSTS, AND RESEARCH PRACTICE

Informed consent procedures for emergency interventional TBI & stroke research
Panel 2: Search strategy and selection criteria
We searched PubMed and Ovid MEDLINE using several strategies. To be informed about the used consent procedures in current traumatic brain injury and ischaemic stroke emergency research practice, we used a representative selection of randomised controlled trials. Data on study design and used consent procedures were extracted. Details on the search strategies, article selection procedures, data extraction, and synthesis of results can be found in the appendix p 3–17. We found articles on the theoretical and conceptual aspects of consent procedures specifically for patients with traumatic brain injury and stroke using search terms, including ‘informed consent’, ‘brain injuries’, ‘head injuries’, and ‘stroke’ (appendix p 18). We focussed on theoretical and conceptual articles
about the most commonly used consent procedures (appendix p 20). This search strategy formed the evidence base for this Personal View.
Table. Consent procedures used in randomised controlled trials on traumatic brain injury and ischaemic stroke
Type of consent reported
Patient informed consent before medical intervention
Proxy informed consent before medical intervention
Deferred consent
Exception from informed consent Waiver of informed consent
Physician consent or other consent type
Traumatic brain injury (N=70)
61 (87%) 15 (25%)
56 (92%)
8 (13%) 6 (10%)
2 (3%)
Ischaemic stroke (N=76)
71 (93%) 68 (96%)
63 (89%)
3 (4%) 5 (7%)
2 (3%)
9
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