Page 112 - Reconstructive Techniques in Musculoskeletal Tumor Surgery

Chapter 5
Appendices
Table A-1. Univariate Cox regression analysis for the time to failure (n = 15) and time to full weight-bearing
(n = 49).
Covariates
Time to failure Infection Fracture
Patient age of ≥18 years Osteosynthesis: bridging plate(s)
Localization within bone piece: diaphyseal
Allograft length of ≥15.0 cm Time to full weight-bearing
Nonunion
Osteosynthesis: intramedullary nail only Adjuvant radiation therapy
All localizations
Lower extremity
Hazard ratio* p-value
-- 4.67 (1.17 - 18.66) 0.02 9.46 (1.18 - 75.71) 0.03 0.15 (0.02 - 1.23) 0.08 4.08 (0.85 - 19.68) 0.08
9.00 (1.12 - 72.07) 0.04
Hazard ratio*
3.12 (0.95 - 10.20) 2.81 (0.94 - 8.41) 6.66 (1.47 - 30.11) 0.11 (0.01 - 0.82) 2.83 (0.86 - 9.30)
2.80 (0.86 - 9.11)
- - -
p-value
0.06 0.06 0.01 0.03 0.08
0.09
- - -
0.36 (0.18 - 0.74) 0.27 (0.09 - 0.77) 0.42 (0.16 - 1.08)
<0.01 0.02 0.07
*The values are given as the hazard ratio, with the 95% CI in parentheses.
Table A-2. Multivariate Cox regression analysis for the time to failure
All localizations
Lower extremity
Covariates
First analysis
Patient age of ≥18 years Osteosynthesis: bridging plate(s)
Second analysis
Patient age of ≥18 years
Localization within bone piece: diaphyseal
Third analysis
Patient age of ≥18 years Allograft length of ≥15.0 cm
Fourth analysis
Localization within bone piece: diaphyseal
Osteosynthesis: bridging plate(s)
Hazard ratio*
5.66 (1.25 - 25.68) 0.13 (0.02 - 0.98)
5.57 (1.18 - 26.32) 1.78 (0.53 - 6.02)
5.65 (1.21 - 26.27) 1.91 (0.58 - 6.37)
2.85 (0.86 - 9.47) 0.11 (0.01 - 0.82)
p-value
0.03 0.05
0.03 0.36
0.03 0.29
0.09 0.03
Hazard ratio*
p-value
8.23 (1.03 - 66.03) 0.05 0.19 (0.02 - 1.48) 0.11
7.45 (0.91 - 61.28) 0.06 2.72 (0.55 - 13.46) 0.22
6.45 (0.79 - 52.67) 0.08 6.01 (0.74 - 49.04) 0.09
3.70 (0.77 - 17.87) 0.10 3.70 (0.77 - 17.87) 0.09
*The values are given as the hazard ratio, with the 95% CI in parentheses.
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