Page 106 - Reconstructive Techniques in Musculoskeletal Tumor Surgery

Chapter 5
In univariable Cox regression analysis for in uence on time to failure, bridging plate xation (HR, 0.11) and patient age of eighteen years or older (HR, 6.66) were the most important factors (see appendix). For lower-extremity reconstructions, patient age of 18 years or older (HR, 9.46) and allograft length of ≥15 cm (HR, 9.00) were related to a shorter time to failure ( gure 5; see appendix). In multivariable analysis, patient age of 18 years or older was the most important factor in uencing time to failure (see appendix). Its in uence was also signi cant in multivariable analyses with infection (HR, 6.22 [95% CI, 1.37 to 28.20]; p = 0.02), fracture (HR, 8.27 [95% CI, 1.79 to 38.16]; p < 0.01), and nonunion (HR, 6.43 [95% CI, 1.42 to 29.18]; p = 0.02).
Figure 5. A line graph showing Cox regression analysis for the in uence of patient age of eighteen years or more on the time to failure.
Complication Rates
During follow-up, 137 complications occurred in 66 patients (76%). Forty patients (46%) had two or more complications. With regard to major complications, 35 patients (40%) had nonunion, 25 patients (29%) had fracture, and 12 patients (14%) had infection. As for the time at which the di erent complications tended
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