Page 194 - Demo

Chapter 7192Abstract22q11.2 deletion syndrome (22q11.2DS) is associated with an elevated genetic risk of several psychiatric disorders. The prevalence of posttraumatic stress disorder (PTSD) has however been reported to be only 0.9%; lower compared to the general population. We explored occurrence of PTSD and traumatic events in a Dutch cohort of 112 adults with 22q11.2DS. PTSD was reported in 8.0%, traumatic events in 20.5%, and trauma-focused treatment in 17.9% of patients. Our novel findings suggest PTSD may be underdiagnosed in 22q11.2DS. Clinicians and other caregivers should be alert to trauma in this population in order to enable treatment and minimize psychiatric burden.