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variable. Odds ratios with 95% confidence interval were calculated. All analyses were performed at a significance level of 5%. The statistical package STATA version 12 was used.
RESULTS
Demographics and clinical characteristics
In total 78 patients in the SpA group and 156 individuals in the healthy control group were matched by age and gender. In the SpA group the mean age was 39.6 (11), 60% were men and the distribution by subtypes was as follows: ankylosing spondylitis (AS) (n=25), non-radiographic axSpA (nr-axSpA) (n=41) and pSpA (n=12). Patients with SpA had a mean disease duration of 5.0 (7.1) years and ASDAS of 2.7 (0.8). Of the SpA patients 45% was HLA-B27-positive. In total, 82% of SpA patients were receiving nonsteroidal anti-inflammatory drugs (NSAIDS) and 49% were receiving sulphasalazine.
Periodontal clinical assessment
In the group of SpA, 56% had a diagnosis of periodontitis, compared with 69% in the control group (p=0.01), according to the parameters of the CDC/AAP. In total, 2.6% had severe periodontitis in contrast to 12.2% in the control group (p=0.01). CAL was less severe in SpA (1.9 (0.6) mm) as compared to controls 2.4 (0.8) mm (p=<0.001). Additionally, the total in-mouth insertion level was found to be lower in SpA patients 2.4 (0.5) mm in comparison to their matched controls 2.9 (0.8) mm (p=<0.001). Results are presented in table 1. In the logistic regression analyses, periodontitis was not positively but negatively associated with SpA (OR=0.57, CI 95% [0.32–1.00], p=0.05).
Antibodies and bacterial identification
There was no significant increase of frequency with regard to IgG1 / IgG2 antibodies against P. gingivalis and the presence of periodontopathic bacteria between SpA patients and healthy controls (Table 1).
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