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ABSTRACT
Objective To compare the frequency and severity of periodontitis in SpA-patients with healthy- control individuals, through the evaluation of clinical, serological and microbiological periodontal condition.
Methods Patients with a diagnosis of SpA (n=78) and bDMARD-naive fulfilling the ASAS classification criteria as well as 156 healthy-controls matched for age/gender, were included. Two trained and calibrated periodontologists performed the periodontal clinical assessment. The presence of periodontitis and its severity were determined according to the criteria established by the Center for Disease Control and Prevention-American Academy of Periodontology (CDC-AAP). The clinical periodontal variables, IgG1/IgG2 antibodies against P. gingivalis and periodontopathic bacterial identification, were also established. Comparisons of periodontal characteristics between the SpA-patients and the control-group were performed using univariable analyses. A logistic regression analyses was performed to calculate the odds ratio (95% CI) for diagnosis of periodontitis in SpA-patients and matched-controls.
Results A diagnosis of periodontitis was established in 56% in SpA patients vs. 69% of healthy- controls (p=0.01). Severe periodontitis was found in 3% vs 12% in SpA vs healthy-controls respectively (p=0.01). There was no significant increase of frequency of any periodontal variable, IgG1/IgG2 antibodies against P. gingivalis or the presence of periodontopathic bacteria between SpA patients and control-group. Periodontitis was not positively associated with a diagnosis of SpA (OR: 0.57 95% CI 0.32-1.00, p=0.05) in the logistic regression analyses.
Conclusions We found a lower rather than a higher frequency and severity of periodontitis in SpA patients in comparison to healthy-control individuals. Our findings suggest that there is no positive association between SpA and periodontitis in Colombian patients.
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