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Prevalence data obtained from the general population of Argentina, Colombia and México were standardized for TB and malignancies. Specific prevalence data for TB stratified for gender and age categories have been obtained for the three countries using the 2015 Global Tuberculosis-report 15. This report is an initiative of the World Health Organization that provides comprehensive infor- mation on the status of the disease at global and country levels. Regarding malignancies, gender- and age-group specific prevalence data have been obtained for the three countries using the 2012 GLOBOCAN-project 16, 17. This initiative provides prevalence estimates for the major types of cancer worldwide.
Statistical analyses
Descriptive statistics were used for the demographic data, disease characteristics, disease activity, risk factors and the comorbidities of the patients included in the analyses. Data are presented as numbers (%) for qualitative variables and as the mean (SD) for continuous variables. The data were stratified for age categories and for males and females separately by comparing expected (general- population) versus observed (Latin America) frequencies. Data from the Global ASAS-COMOSPA- study was included for comparison with LA countries. In addition 95%CIs were estimated using the method described by Wilson 18, which is considered an accurate and precise method for calculating Cis 19 . Standardised risk-ratios (SRR) were determined to compare event rates (in this study, comorbidities and risk factors) in SpA patients vs. the general-population. SPSS Statistics 22 was used to perform the statistical analyses.
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