Page 59 - SPONDYLOARTHRITIS IN COLOMBIA -

Table 3. Comparison of demographic and SpA disease characteristics according to HLA-B27- ordered status (n=581)
HLA-B27 ordered
Explanatory variables Yes (n=441) No (n=140) p-value
HLA-B27 ordered
Male gender, (%)
Age at assessment, (years)*
Age symptom onset (≤35 years) (%)*
Symptoms at presentation (%)* Arthritis
Enthesitis
Back pain
Buttock pain Several symptoms
Disease duration (≤5 years) (%)*
Chronic back pain, (%) IBP, (%)
Buttock pain, (%) Arthritis, (%) Enthesitis, (%) Dactyilitis, (%) Uveitis, (%)
Psoriasis, (%) Infection history, (%) BASFI (≥4) (%)*
BASDAI (≥4) (%)* ASDAS CRP (high) (%)* ASDAS ESR (high) (%)* CRP (≥5 mg/dl) (%)* ESR (≥20 mm/hr) (%)*
Diagnostic subtype (%) Ankylosing spondyltis Undifferentiated SpA
Reactive arthritis Psoriatic arthritis IBD
Number of SpA features Number of criteria met
311 (70.5)
34.4 ± 12 (n=367) 361 (81.9) (n=364)
124 (28.1) 25 (5.7) 191 (43.3) 8 (1.8) 87 (19.7) (n=373) 132 (29.9) (n=344) 341 (77.3) 207 (46.9) 136 (30.8) 313 (70.9) 255 (57.8) 61 (13.8) 32 (7.3) 17 (3.9) 153 (34.7) 353 (80) (n=291) 366 (82.9) (n=291) 407 (92.3) (n=116) 403 (91.4) (n=222) 43 (9.8) (n=142) 333 (75.5) (n=239)
134 (30.4) 179 (40.6) 108 (24.4) 12 (2.7)
3 (0.7) 2.1 ± 1.1 2.1 ± 0.9
106 (75.7) 0.23
35 ± 12.3 0.70 (n=98)
119 (85) 0.39 (n=98)
81 (57.9) 7 (5) 32 (22.9) 1 (0.7) 19 (13.5) (n=98)
≤0.001
43 (30.7) 0.86 (n=89)
98 (70) 0.07
51 (36.4) 0.02
36 (25.7) 0.24 106 (75.7) 0.27 77 (55) 0.55 23 (16.4) 0.44 3 (2.1) 0.02 10 (7.1) 0.10 57 (40.7) 0.19 119 (85) 0.19
(n=75)
117 (83.6) 0.87
(n=75)
138 (98.6) 0.02
(n=23)
134 (95.7) 0.15
(n=36) 112 (80) (n=36)
≤0.001
117 (83.6) 0.04 (n=63)
35 (25) 0.13 51 (36.4)
44 (31.4)
9 (6.4)
1 (0.7)
1.8 ± 1.1 0.36
1.8 ± 1 0.23
Values are mean ± SD for continuous variables or percentages for categorical variables, unless otherwise specified. p-values were calculated using t-test adjusted for unequal variances for comparison of continuous variables and Chi square test for categorical variables.
IBP, inflammatory back pain, CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; IBD, SpA associated to Inflammatory Bowel Disease; MRI, magnetic resonance imaging; BASFI, Bath Ankylosing Spondylitis Functional Index; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; ASDAS, Ankylosing Spondylitis Disease Activity Score.
* Variables with missing data, n means the number of patients in which these variables are based
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