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the principles of Helsinki declaration. Patients signed informed consent to collect, file and use the data.
Demographic, clinical and imaging characteristics
The following information was included in the database: patient demographics, spinal mobility measures (occiput to wall distance, chest expansion, modified Schober test, lateral spinal flexion), laboratory tests [C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and HLA-B27 testing]; age at assessment, age at first symptoms, symptom duration, family history of SpA and the history (past) and presence (current) of chronic back pain (more than 3 months), inflammatory back pain, alternating buttock pain, asymmetric oligoarthritis (predominantly in lower limbs), enthesitis (heel pain), dactylitis (“sausage-shape” digit), uveitis (confirmed by ophthalmologist) and psoriasis. Functional capacity and disease activity were measured by the BASFI 12 and BASDAI13, respectively. The Ankylosing Spondylitis Disease Activity Score (ASDAS), was also calculated: ASDAS-ESR and ASDAS-CRP14. Acute phase reactants, HLA-B27, and the results of plain radiographs and MRI of sacroiliac joints (SI) were retrieved from the clinical file, as requested by rheumatologist. All data was collected at the initial visit to the clinic. Data related to follow-up were not included.
The rheumatologist interpreted the radiographs according to the modified New York classification for radiographic sacroiliitis 15. Sacroiliitis on MRI was defined according to the local experienced musculoskeletal radiologist’s interpretation of the presence of active inflammatory changes in the SI-joint 16. This is according usual clinical practice (no central reading was done). The rheumatologists assessed the patients in the clinic and provided the clinical diagnosis of SpA categorized by subtypes: AS, uSpA, ReA, PsA and IBD. It was recorded in the clinical file and used as the external standard to test against.
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