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Participants
A sample of patients from a rheumatology outpatient clinic in Colombia were invited to complete the ASAS-HI. Adult SpA patients fulfilling the ASAS classification criteria either axial or peripheral were eligible for participation. According to the ASAS international validation study 6 a convenient sample was obtained: at least 80% of patients with axSpA and a maximum of 20% with pSpA. Estimated proportion of axSpA patients were approximately 40% with nr-axSpA and 60% with AS. The institutional ethics committee approved the study. Informed consent was obtained from all participating patients.
Assessments
Demographic and clinical information was collected in the first visit (baseline) including age, gender, years of formal education, work status, presenting symptoms, extra articular manifestations and current results of laboratory test for C-reactive protein (for ASDAS) 9. To assess the different disease aspects of health, patients were asked about their disease duration (symptoms duration), current medication and completed the patient global assessment (NRS), pain (NRS), spinal pain (NRS), the Bath Ankylosing Spondylitis Disease Index (BASDAI) 10, the Bath Ankylosing Spondylitis Functioning Index (BASFI) 11, EuroQol five dimensions questionnaire (EQ-5D) 12, Short Form Survey Instrument 36-Item (SF-36) 13, Hospital Anxiety and Depression Scale (HAD-S) and ASAS-HI.
Reliability
A subsample of patients with no change in treatment (no change in NSAIDS over last week, no change in DMARD or TNF blockers over last 4 weeks) who considered themselves in a stable disease state were invited to complete the questionnaire at home after 4-7 days interval to evaluate reproducibility (reliability arm).
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