Page 100 - SPONDYLOARTHRITIS IN COLOMBIA -

ABSTRACT
Objective To validate a Spanish-language translation of the ASAS Heath-Index (ASAS-HI) testing its reliability, construct validity and responsiveness in Colombian-patients with spondyloarthritis. Methods Translation was done following a forward-backward procedure. Patients fulfilling the ASAS criteria for either axial or peripheral-SpA participated. Test-retest reliability was assessed by intraclass correlation coefficient (ICC) in patients without treatment changes. In patients who required a therapeutic intervention, responsiveness was assessed using the standardized response mean (SRM). Construct validity was evaluated by Spearman correlation. Internal consistency (Cronbachs-α) and discriminative ability of the ASAS-HI were assessed.
Results Fifty patients were included: 54% male, mean (SD) age 44.8(13.1), symptom duration 15.8(9.7) years, BASDAI 4.6(2.2), BASFI 4.7(2.5), ASDAS-CRP 2.2(1.0). AxSpA was established in 44 patients (AS=30, nr-axSpA=14) and pSpA in 6. The score of the ASAS-HI was 8.2(5.1). The test-retest reliability was good with an ICC of 0.84. SRM was 2.58 (1.75-3.37) in 10 patients with any intervention and 2.94 (2.13-4.24) for 7 patients starting TNF-blockers. Construct validity showed a good correlation between ASAS-HI and pain, BASDAI, BASFI, and ASDAS (r≥0.60). A high internal consistency was found with a Cronbachs-α of 0.91. ASAS-HI discriminated well between patients with different stages of disease activity (BASDAI and ASDAS). Those with higher disease activity had higher ASAS-HI scores.
Conclusion The Spanish-language translation of the ASAS-HI has proven to be psychometrically valid for Colombian-patients with SpA. This version is available to evaluate the state of health and functioning in these patients and can be used in clinical practice.
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