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Acknowledgements
The authors acknowledge the doctoral research scholarship provided by the Federal Government of Nigeria (TETFUND) in conjunction with the Nasarawa State University, Keffi (NSUK), Nasarawa State.
Author Contributions
Conceptualization, M.P.P., M.F.B., M.J.B and C.A.S; Methodology, K.P., and G.M.F; Investigation, A.I.A and L.B.; Writing – Original Draft , A.I.A.; Writing – Review & Editing, M.P.P., G.M.F., and M.F.B; Supervision M.P.P, and C.A.S.
Declaration Of Interests
The authors declare no competing interests.
References
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2. Briscoe, J. and S. Small, Morphogen rules: design principles of gradient- mediated embryo patterning. Development, 2015. 142(23): p. 3996-4009.
3. Petrova, R. and A.L. Joyner, Roles for Hedgehog signaling in adult organ homeostasis and repair. Development, 2014. 141(18): p. 3445-57.
4. Petersen, C.P. and P.W. Reddien, Wnt signaling and the polarity of the primary body axis. Cell, 2009. 139(6): p. 1056-68.
5. Barker, N., The canonical Wnt/beta-catenin signalling pathway. Methods Mol Biol, 2008. 468: p. 5-15.
6. Hardwick, J.C., et al., Bone morphogenetic protein signalling in colorectal cancer. Nat Rev Cancer, 2008. 8(10): p. 806-12.
7. van den Brink, G.R. and G.J. Offerhaus, The morphogenetic code and colon cancer development. Cancer Cell, 2007. 11(2): p. 109-17.
8. Merchant, J.L., Hedgehog signalling in gut development, physiology and cancer. J Physiol, 2012. 590(Pt 3): p. 421-32.
9. Petrov, K., B.M. Wierbowski, and A. Salic, Sending and Receiving Hedgehog Signals. Annu Rev Cell Dev Biol, 2017. 33: p. 145-168.
Chapter 4
Chapter 4
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