Page 45 - Physical activity in recipients of solid organ transplantation - Edwin J. van Adrichem

obtained if all predictor variables were defaults.
represent the di
Physical activity in recipients of solid organ transplantation
!
e
ects.

e intercept of the model represents the estimated 6MWD that would be
erence between 6MWD and the reference category (categorical data) or
hats of the variables in the model

the change in 6MWD that was expected with 1-unit change in a given variable
(continuous variables).
Di

erences between recipients reaching 82% of the predicted 6MWD and
recipients not reaching this distance were analyzed. Categorical variables were tested with
the chi-square test, and for continuous data, the Student t test or the Welch t test was used.
Variables at discharge that were signi

cantly related to “reaching 82%” at 12 months after
LTx were entered into a logistic regression analysis (backward method). Two-sided
signi

cance tests were used (alpha <.05). Analyses were performed with statistical
programming language R (version 2.12.0) and IBM SPSS statistical software (version 20.0,
IBM SPSS, Armonk, New York).
Results
Characteristics of Study Sample
e

1).
e initial database comprised 269 patients, 111 of whom met the inclusion criteria (Fig.

ree patients were excluded from the analyses because of the limited representation of
after leukemia treatment, and 1 patient was diagnosed with histiocytosis X).

e mean age
at transplantation of the 108 included recipients was 51.5 years (SD=11.3), 49 (45.4%)
were men, and the median waiting list time was 505 days (interquartile range=191-86l).
Double lung transplantation was performed in 90 recipients (83-3%).

e recipients were
grouped as follows: approximately half in the COPD group (53 [49.1%]), 11 (10.2%) in
the pulmonary vascular disease group, 16 (14.8%) in the CF group, and 28 (25.9%) in the
pulmonary

brosis group.
their conditions (2 patients received a transplantation because of graft-versus-host disease
Figure 1.
Flowchart of inclusion of recipients of lung transplantation in data analysis. TX=transplantation.
43.
3