Page 135 - Physical activity in recipients of solid organ transplantation - Edwin J. van Adrichem

in
Physical activity in recipients of solid organ transplantation
Results
Cardiopulmonary response
Baseline characteristics of the transplant participants and controls (Tables 2 and 3) did not
signi

cantly vary for age (p = .186), gender (p = .716), BMI (p = .089), VO2max (p = .521),
and peak load (p = .351).
With increasing altitude, a similar decrease in oxygen saturation was seen in the transplant
participants and the control group (Fig 1A). Results of the LMM showed that transplant
participants did not have signi

cantly di

erence between transplant participants and controls. Heart frequency was signi

uenced by gender (female > male) and altitude. PM heart frequency was lower than AM
heart frequency (borderline signi
participants showed relatively stable values, the control group demonstrated a more
uctuating course (Fig 1C). No signi
015). No signi
cant di

erent saturation levels. Factors that signi
cance, p = .045, Table 4).

cantly
contributed to decreasing saturation levels were increasing age and increasing altitude. PM
saturations were signi

cantly lower than AM saturations (Table 4).

e course of heart frequency showed a gradual increase (and decrease) along with
the increase (and decrease) of altitude (Fig 1B).

e LMM showed no signi

cant
di

cantly
Analysis of blood pressure indicated that systolic blood pressure (SBP) initially
increased in all subjects followed by a minimal decrease in the second half of the climb.
Diastolic blood pressure (DBP) showed a comparable pattern, however, where transplant

participants and the controls for SBP and DBP. Factors that did signi

SBP and DBP were altitude and time of day; PM SBP and DBP values were signi
higher than AM values (Table 4). One transplant participant and one control experienced
increase in altitude. LMM analysis showed that LLAMS scores were signi
cant di
Altitude sickness scores on the LLAMS questionnaire increased gradually with the

erences were found between the transplant

cantly in

uence

cantly
high blood pressure (DBP > 115 mmHg) for which they received nifedipine.
Altitude sickness scores
erences in altitude sickness scores were determined between

cantly higher
than values at sea level for all measurements between 1640 and 3900 meters (p = < .001 to .

transplant participants and controls (p = .916). However, one of the returning transplant
participants exhibited symptoms of hypothermia and/or altitude sickness whereas no
participant in the control group displayed symptoms of such severity that it limited the
summit attempt.

cant di

erence in LLAMS scores
between male and female (
e analysis showed an additional signi
Beta
participants. Borg scores for perceived exertion did not signi
= 0.6, p = .007) indicating higher LLAMS scores in female

cantly di

er between
transplant participants (median (interquartile range (IQR))) 6 (6– 9) and controls 6 (6–9),
p = .983.
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