Page 159 - The role of advanced echocardiography in patients with ischemic heart disease - Rachid Abou

defined as total cholesterol 190 mg/dl or previous pharmacological treatment. Diabetes mellitus was defined as fasting blood glucose ≥7.0 mmol/L, 2-h oral glucose tolerance test glucose ≥11.1 mmol/L or previous pharmacological treatment.
Left ventricular mechanical dispersion and scar burden
Table 3 demonstrates the findings from 2D echocardiography and LGE-CMR data. The median interval from index infarction to echocardiography was 104 days (IQR 92-181), whereas the median interval from index infarction to LGE-CMR was 74 days (IQR 51- 132). The mean LVEF for the study population was 49±10% and the mean LV GLS was -14.5±3.8%. In addition, the median LV MD was 53.5 ms (IQR 43.4-62.8).
On LGE-CMR, the total scar burden was 11.4% (IQR 3.8-17.1), the percentage of infarct core tissue was 6.2% (IQR 2.0-12.7) whereas the median extent of the border zone was 3.5% (IQR 1.5-5.7) (Table 3). LV MD was significantly correlated with infarct core (r=0.517, p<0.001), total scar burden (r=0.497, p<0.001) and border zone (r=0.298, p=0.003).
Table 2. Medical management of the study population.
Medications at discharge
Aspirin, n (%) Thienopyridines, n (%) ACEi/ARBs, n (%) β-blockers, n (%) Statins, n (%)
Device therapy
ICD, n (%)
CRT, n (%)
Index infarction to CRT (days)
91 (95) 96 (100) 93 (97) 93 (97) 96 (100)
4 (4)
6 (6)
208 (132-1145)
8
Variable
Total population (n=96)
Data are presented as mean ± standard deviation, number (percentage) or as median (25th-75th percentile). ACE = angiotensin converting enzyme; ARB = angiotensin receptor blocker; CRT= Cardiac resynchronization therapy; ICD= implantable cardioverter defibrillator
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