Page 132 - Cellular Imaging in Regenerative Medicine, Cancer and Osteoarthritis
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                                 Chapter 6
 Figure 3 Uptake and internalization of [111In]In-Albutate-1 and [111In]In-DOTA-TATE in U2OS-SSTR2 cells.
2.4. In vivo biodistribution
Biodistribution studies were performed at 5 different time points after injection of [177Lu]Lu-Albutate-1 (30 MBq/240 pmol) (Figure 4). At 1 h post injection the activity level of [177Lu]Lu-Albutate-1 in the blood was 58.59 ± 6.30%ID/g and
Figure 4 Biodistribution of [177Lu]Lu-Albutate-1 in blood, organs and tumor. 30 MBq/240 pmol [177Lu] Lu-Albutate-1 (for 24h +/- block) was injected i.v. in mice and biodistribution was determined at 1, 24, 48, 72 and 168 h after injection. The amount of radioactivity in the tissue samples was determined and calculated per gram.
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