Page 79 - Risk quantification and modification in older patients with colorectal cancer
P. 79

                                Geriatric risk score and poor surgical outcomes
  1,0
0,8
0,6
0,4
0,2
0,0
          0
365 730
Overall Survival in days
  VMS Risk sumscores
Low Risk Intermediate Risk High Risk
       Low Risk sumscore: Reference Intermediate Risk sumscore: HR 1.9 (1.1-3.5), p=0.03 High Risk sumscore: HR 8.7 (4.0-19.2), p<0.001
Figure 1 Overall survival stratified by the VMS risk sumscores
Secondary outcomes
One hundred ninety-one patients (35%) had one or more complications: 16% had surgical complications (n=87), 9% cardiopulmonary complications (n=48) and 6% suffered from delirium (n=34). Mean length of stay was 8.7 days (±7.0 days standard deviation, SD). Forty-eight patients (9%) were readmitted within 30 days after discharge, and 98 patients (18%) were discharged to a nursing home or rehabilitation centre. The complication rate (any complication) -was 28.7% in the low risk group, 40.9% in the intermediate risk score group and 51.9% in the high risk group (Appendix B).
In the multivariate model, intermediate risk sumscore (OR 1.8;(95% CI 1.2- 2.7, p=0.003) and high risk sumscore (OR 2.4; (95% CI 1.0-5.5, p=0.04) were both associated with complications. Intermediate risk score was also independently associated with delirium (OR 2.9; 95% CI 1.3-6.4, p=0.009) and discharge not to home (OR 2.7; 95% CI 1.6-4.5, p<0.001). We could not find an independent association between the risk sumscore and surgical complications, cardiopulmonary complications, or readmission.
Page 1
77
4
 Proportion Overall Survival














































































   77   78   79   80   81