Page 40 - Imaging of Osteoarthritis and Rheumatoid Arthritis in Hand Joints

Chapter 2
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Table 4. Change and responsiveness of US and Scintigraphy studies for Hand OA
Author (year)
Intervention
Time between examinations
Imaging feature examined
Comparator
Responsiveness (comparison between both changes)
US studies
Keen (2010)43
i.m. prednisolon
Pain VAS
Klauser (2011)44
i.a. hyaluronic acid
68
Scintigraphy Studies
Balblanc (1995)32
No intervention No intervention No intervention
4 years 2 years 1 year
isotope uptake
0-18 7.2 0-90 16.1
— 4.7
OA CR score 0-135
13.8 68.7 48.4
r=0.13 (p<0.05) NA
NA
Olejárova (2000)50
isotope uptake
— 9.10
OA CR score 0-300
64.0 — 39.7 —
Macfarlane (1993)28
isotope uptake
0-34 21.9 0-136 41.9
— 20.0
— 37.8
Pain VAS 0-100
4 weeks
synovitis PD
0-14 6.5 0-42 9.4 0-14 1.1 0-42 1.9
— 6.1
— 9.0 0-100
— 0.9
— 1.5
65
— 29
— 37
NA
4 weeks
effusion PD
mm* 15.6 0-3 2.7
— 13.2 Pain VAS
— 1.4 0-100 68
r=0.7 (p<0.001) r=0.8 (p<0.001)
Type
Score Mean scores range baseline — follow-up
Type and score range
Mean scores baseline — follow-up
Results are given as the values at baseline and the values at the second measurement.
*= scored in millimetres, no range predefined.
i.m. = intramuscular; i.a. = intra-articular; PD = Power Doppler ; CR = conventional radiography; VAS = visual analogue scale; NA = not available
— 11.9 —
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