Page 35 - Imaging of Osteoarthritis and Rheumatoid Arthritis in Hand Joints

Table 2. Validity of US, MRI and scintigraphy studies for hand OA.
Author (year)
US studies
Arrestier (2011)31
Iagnocco (2000)37
Keen (2008)42
Mancarella (2010)60
US studies
Arrestier (2011)31
Iagnocco (2005)38
Keen (2008)41
Vlychou (2009)51
Wittoek (2010)52
Kortekaas (2011)46
US studies
Kortekaas (2011)46
Kortekaas (2010)45
US studies
Arrestier (2011)31
US studies
Keen (2008)42
Pathology examined positive positive joints Statistics (joints scored) joints comparator
(mean) (mean)
healthy controls
synovitis (16) 0.0 0.0 effusion PIP (8) 2.1 1.7 effusion DIP (8) 2.1 0.2 subtendinous 1.9 - effusion PIP (8)
PD PIP (8) 0.1 0.0 PD DIP (8) 0.3 0.0
effusion (1) 3.55a 2.89
JSN (30) 12.1 8.2 osteophytes (30) 12.2 8.8 synovitis (30) 13.7 10.2 PD (30) 2.0 0.9
synovitis (28) 3.2 2.1 effusion (28) 3.0 1.9 PD (28) 2.3 0.1 cartilage thickness 0.35a 0.41 (mm)
CR
effusion (16) 4.1 c PD (16) 0.4 c
erosions (1) 0.15 0.20d
osteophytes (30) 12.1 8.9e JSN (30) 12.2 7.1e
erosions (30) 10.5 5.2 d osteophytes (30) 16.4 14.1 d
erosions (18) 3.1 1.9f osteophytes (18) 11.0 8.1f
osteophytes (30) 20.7 13.8g
- p>0.05 p<0.05 p>0.12
- -
p<0.001
p<0.001 p<0.001 p<0.001 p=0.002
p=0.06 p=0.08 p<0.0001 p<0.0001
κ=0.03 κ=0.01
κ=0.54 κ=0.44
p<0.05 p<0.05
2
osteophytes (30) 20.7 NR
synovitis (30) 6b 9b joint effusion (30) 6b
synovial thickening (30) 2b
PD (30) 2b
OR 4.8 (3.1 – 7.5)
OR 4.0 (1.9 – 8.2) OR 3.7 (1.8 – 7.6) OR 2.5 (1.1 - 6.3) OR 2.0 (0.8 - 4.9)
effusion (16) 4.1 2.0 PD (16) 0.4 2.0
joint pain (VAS)
JSN (30) 12.1 65 osteophytes (30) 12.2
synovitis (30) 13.7
PD (30) 2.0
κ=0.14 κ=0.06
ρ=0.13 ρ=0.05 ρ= 0.001 ρ=-0.31
Systematic review of advanced hand OA imaging
pain on palpation
joint pain with swelling
Se=0.73 Sp=1.00
Se=0.83 Sp=0.76 Se=0.82 Sp=0.72
Se=0.94 Sp=0.92 Se=0.95 Sp=0.66
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