Page 58 - Advanced echocardiography in characterization and management of patients with secondary mitral regurgitation
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Chapter three. Prognostic Value of Left Ventricular Global Longitudinal Strain
Figure 3. Kaplan-Meier Curves for All-Cause Mor- tality
Time to all-cause mortal- ity, according to baseline LV GLS: ≥7.0% (less im- paired, green) and LV GLS <7.0% (more impaired, red). Abbreviations as in Figure 1.
Table 4. Univariable and Multivariable Cox Regression Analyses to Identify Associates of All- Cause Mortality
 Univariate Analysis HR 95% CI 1.030 1.018–1.041 1.530 1.201–1.948 1.004 1.003–1.004 0.899 0.719–1.123 1.187 0.956–1.475 1.329 1.031–1.712 1.344 1.082–1.669 1.122 0.644–1.955
p Value
Multivariate Analysis HR 95% CI 1.031 1.018–1.044 1.256 0.954–1.654 1.003 1.002–1.004
p Value
  Age
Male
Creatinine
Hypertension
Atrial fibrillation
Diabetes mellitus
Ischemic etiology
NYHA functional
class ≥II
Beta-blockers
Diuretics
CRT
Invasive mitral
treatment
LAVI
TAPSE
LVEDVi
E′
LVEF ≤30%
LV GLS <7.0%
CI = confidence interval; HR = hazard ratio; other abbreviations as in Tables 1, 2, and 3.
∗ Device implanted before invasive mitral valve treatment. † Combined surgical MVr, MVR, and percutaneous edge-to-edge MVr.
0.803 0.641–1.007 1.994 1.411–2.818 1.171 0.904–1.517 1.071 0.854–1.342
0.057 <0.001 0.231 0.554
0.001 0.007 <0.001 0.046 0.007 <0.001
1.010 1.004–1.016 0.966 0.943–0.991 1.005 1.003–1.008 0.941 0.886–0.999 1.392 1.096–1.769 1.548 1.246–1.922
1.006 1.000–1.013 1.002 0.975–1.029 1.004 1.000–1.007 0.956 0.895–1.022 1.055 0.794–1.403 1.337 1.038–1.722
<0.001 0.001 <0.001 0.348 0.121 0.028 0.008 0.685
1.397 1.070–1.826 1.105 0.864–1.414
1.614 1.128–2.309
<0.001 0.104 <0.001
0.014 0.425
0.009
0.065 0.905 0.030 0.188 0.711 0.024
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