Page 73 - Strategies for non-invasive managementof high-grade cervical intraepithelial neoplasia - prognostic biomarkers and immunotherapy Margot Maria Koeneman
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HLA as a prognostic biomarker
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Case Regression
HPV geno- typing (HPV 16
or other)
HLA-A* HLA-A*
HLA-B* HLA-B*
HLA-C* HLA-C*
HLA- HLA- HLA- HLA- HLA- HLA- HLA- HLA- DRB1* DRB1* DRB3/4/5* DRB3/4/5* DQA* DQA* DQB* DQB*
224 Yes
225 No
226 No
229 Yes
231 No
232 No
246 Yes 248 Yes 250 No
OTHER OTHER OTHER OTHER OTHER HPV16 OTHER OTHER OTHER
02 03 02 - 02 23 01 11 23 32 01 03 02 68 02 32 01 24
15 40 08 40 44 55 08 15 35 40 07 - 14 15 18 51 37 39
03 - 03 07 03 05 04 07 03 04 07 - 03 08 07 15 06 07
04 08 4*01 -
03 13 3*01 3*03 04 - 4*01 -
03 04 3*01 4*01 01 14 3*02
15 - 5*01 -
07 14 3*02 4*01 11 13 3*02 3*03 0810X X
03040304 01 05 02 06 03 - 03 - 03 05 02 03 01 X 05 X 01 - 06 - 01 02 02 05 01 05 03 06 01040405
a – indicates that the second allele is identical to the first allele b X indicates that the reaction failed.
