Page 199 - Strategies for non-invasive managementof high-grade cervical intraepithelial neoplasia - prognostic biomarkers and immunotherapy Margot Maria Koeneman

incorporation of the treatment modality in patient information brochures. Remaining knowledge gaps with regard to imiquimod treatment of high-grade CIN are cost-effectiveness and patient and physician satisfaction with imiquimod treatment. These issues could be addressed in future studies. Finally, long-term studies should reveal whether imiquimod indeed reduces long-term side effects of surgical treatment, with emphasis on premature birth after both treatment modalities.
Discussion
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