Page 148 - Strategies for non-invasive managementof high-grade cervical intraepithelial neoplasia - prognostic biomarkers and immunotherapy Margot Maria Koeneman

Chapter 7
19. How serious were the side effects mentioned in the last questions, in general? · No side effects noticed
· Mild side effects
· Moderate side effects · Severe side effects
· Comment: ...
20. Did any of your patients stop imiquimod treatment due to side effects? · Yes
· No
· Comment: ...
21. Would you recommend treatment of VAIN with imiquimod and would you apply it again? · Yes
· No
· Comment: ....
22. Are you aware of the application of imiquimod (Aldara ) for cervical intraepithelial neoplasia (CIN), in literature or clinical practice? Have you ever applied imiquimod for this indication?
· I am aware of this, I have not applied it myself. (to question 36) · I am aware of this, I have applied it myself. (to question 23)
· I am not aware of this. (to question 36)
23. You have applied imiquimod in CIN. How often have you applied it for this indication?
· · ·
24. What · · ·
1-5 times
6-10 times
More than 10 times
was(/were) the lesion grade(s)? Low grade lesion(s) (CIN 1) High grade lesion(s) (CIN 2-3) Both
25. Was it a primary or recurrent lesion? · Primary lesion(s)
· Recurrent lesion(s) · Both
26. What was your rationale for using imiquimod in the treatment of this lesion? (open question)
27. How did you apply the imiquimod? (multiple options possible) · Vaginal capsule
· Vaginal suppository · Vaginal tampon
· Vaginal applicator
· Other: ...
28. What was the dosing scheme and treatment period? (open question)
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