Page 99 - Helicobacter pylori and Gastric Cancer: From Tumor microenvironment to Immunotherapy
P. 99

 10. Pak, E. and R.A. Segal, Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy. Dev Cell, 2016. 38(4): p. 333-44.
11. Ericson, J., et al., Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell, 1996. 87(4): p. 661-73.
12. Buller, N.V., et al., Hedgehog signaling and maintenance of homeostasis in the intestinal epithelium. Physiology (Bethesda), 2012. 27(3): p. 148-55.
13. Youssef, K.K., et al., Identification of the cell lineage at the origin of basal cell carcinoma. Nat Cell Biol, 2010. 12(3): p. 299-305.
14. Gorlin, R.J., Nevoid basal cell carcinoma (Gorlin) syndrome. Genet Med, 2004. 6(6): p. 530-9.
15. Dessaud, E., A.P. McMahon, and J. Briscoe, Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development, 2008. 135(15): p. 2489-503.
16. Bijlsma, M.F., et al., Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites. Cell Signal, 2007. 19(12): p. 2596-604.
17. Tukachinsky, H., et al., Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog. Proc Natl Acad Sci U S A, 2016. 113(40): p. E5866-E5875.
18. Firestone, A.J., et al., Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein. Nature, 2012. 484(7392): p. 125-9.
19. He, M., et al., The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment. Nat Cell Biol, 2014. 16(7): p. 663-72.
20. Kasper, M., et al., Hedgehog signalling in breast cancer. Carcinogenesis, 2009. 30(6): p. 903-11.
21. Kasper, M., et al., Basal cell carcinoma - molecular biology and potential new therapies. J Clin Invest, 2012. 122(2): p. 455-63.
22. Matise, M.P. and A.L. Joyner, Gli genes in development and cancer. Oncogene, 1999. 18(55): p. 7852-9.
23. Karlstrom, R.O., et al., Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development, 2003. 130(8): p. 1549-64.
                                 Noncanonical Hedgehog signaling
Noncanonical Hedgehog signalling
93
97
4
















































































   97   98   99   100   101