Page 119 - Helicobacter pylori and Gastric Cancer: From Tumor microenvironment to Immunotherapy

IM, intestinal metaplasia
Table 8. The association between OLGA gastritis stage and intestinal metaplasia
Helicobacter Pylori
Helicobacter pylori
Table 6: Risk factors-associated with cancer Histological atrophy
Total
75 107 62
Weighted κ value
0.79
endoscopic under- diagnosis
Normal
92
Limited
97
Extended
Normal
Endoscopic Limited (C-1~2) atrophy
Extended (C-3~O-3)
Total
59 248
70
5
24
80
7
12
52
concordance
endoscopic over- diagnosis
Association between OLGA Gastritis Stage, Endoscopic gastric atropy and Intestinal Metaplasia
Intestinal metaplasia, extensive IM, and incomplete IM subtype also clustered to the subgroup of patients with high-stage OLGA gastritis (Table 8).
Table 7. Association between endoscopic gastric atrophy and metaplasia
Endoscopic gastric atrophy
Moderate-to severe None-to-mild P (X2 test) Adjusted Odd (n = 40) (n =38) ratios (95% CI)
Complete IM
27.5% (11/40) 47.34% (18/38) <0.001 21.3 (8.7–35.2)
Incomplete 30.0% (12/40) 31.6% (12/38) <0.001 33.5 (7.4–37.3)
Unidentified 42.5 % (17/40) 36.84(14/38) <0.001 41.7 (4.1–74.1)
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