Page 61 - The role of advanced echocardiography in patients with ischemic heart disease - Rachid Abou
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endocardium is manually traced in the apical 4-chamber view, and the region of interest is adjusted to fit the thickness of the LA wall. Strain curves for individual segments are illustrated. LA reservoir strain is measured as the peak global longitudinal strain during ventricular systole, which is indicated by the dotted line within the strain curves.
Continuous variables are reported as mean ± standard deviation. One-way analysis of variance (ANOVA) was used to compare continuous variables across the groups. Categorical variables are reported as frequencies and percentages and were analysed using the χ2 test. Pairwise comparisons were performed to assess differences across age categories. Uni- and multivariate linear regression analyses were performed to identify clinical, ECG and echocardiographic correlates of LA functional characteristics (PWD, PA-TDI and LA reservoir function). The level of significance for univariate analysis was set at p<0.20. Statistical analysis was performed on SPSS for Windows v20.0 (IBM, Armonk, New York). A 2-tailed p-value of <0.05 was considered statistically significant.
RESULTS
Mean age of the patients was 58 (range 16-91) years old and 188 (49%) were male. The clinical characteristics of the patients divided according to the 5 pre-determined age categories are presented in Table 1. A total of 365 (95%) patients had analysable 12- lead surface ECGs (Table 2). The mean PWD was 43±12 ms for the overall population. A significant increase in the duration of PWD across age categories was observed (p<0.001). In contrast, there was no significant difference in the average P-wave duration across the age categories (p=0.100). PA-TDI duration analysis was feasible in all patients. The mean PA-TDI duration was 129±27 ms in the overall population. PA-TDI duration significantly increased with ageing (Table 3). Analysis of LA reservoir strain was feasible in all patients. The mean LA reservoir strain was 36±13% in the overall population. When analysing the age categories, LA reservoir strain significantly decreased with ageing (Table 3).
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