Page 156 - The role of advanced echocardiography in patients with ischemic heart disease - Rachid Abou
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Chapter eight. LV mechanical dispersion versus LV scar burden
and LV mass were computed automatically. LGE was defined by a signal intensity ≥35% of maximal myocardial signal intensity (total scar burden). In addition, results were subdivided into infarct core (≥50% of maximal signal intensity) and border zone (35%– 50% of maximal signal intensity, which reflects infarct tissue heterogeneity) (Figure 3).4
Figure 2. Left ventricular mechanical dispersion. Example of patient after anterior infarction. Panel A= speckle tracking analysis of apical long-axis ; Panel B= speckle tracking analysis of apical 4-chamber view; Panel C= speckle tracking analysis of apical 2-chamber view. Panel D= Bull’s eye plots for global value of longitudinal strain which is calculated as the average of the 17 regional strain values, Panel E= mechanical dispersion (23.2 msec) with time to peak negative strain in all left ventricular segments.
Follow-up and endpoints
Clinical data were collected from the Cardiology Department Information System (EZIS chipsoft & EPD-Vision; Leiden University Medical Center, Leiden, The Netherlands). The occurrence of ICD therapy was assessed by device interrogation. Appropriate ICD therapy was defined as ICD shocks in response to ventricular tachycardia/fibrillation and anti- tachycardia pacing. Furthermore, all-cause mortality was reported including cardiac and non-cardiac mortality. Patients were followed-up from the moment of admission to the occurrence of the composite endpoint of appropriate ICD therapy and all-cause mortality.
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